| Registro completo |
| Provedor de dados: |
Anais da ABC (AABC)
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| País: |
Brazil
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| Título: |
Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination
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| Autores: |
PEREIRA,FRANCISCO C.
STRADIOTTO,NELSON R.
ZANONI,MARIA VALNICE B.
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| Data: |
2002-09-01
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| Ano: |
2002
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| Palavras-chave: |
Miconazole
Voltammetry
Electroanalysis
Determination
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| Resumo: |
Miconazole is reduced at mercury electrode above pH 6 involving organometallic compound formation, responsible for an anomalous polarographic behavior. The electrodic process presents a large contribution of the adsorption effects. The drug can be determined by cathodic stripping voltammetry from 8.0 x 10-8 to 1, 5 x 10-6 molL-1 in Britton-Robinson buffer pH 8.0, when pre-accumulated for 30s at an accumulation potential of 0V. A relative standard deviation of 3.8% was obtained for ten measurements of 1.0 x 10-7 molL-1 miconazole in B-R buffer pH 8.0 and a limit detection of 1, 7 x 10-8 molL-1 was determined using 60s of deposition time and scan rate of 100 mVs-1. The proposed method is simple, precise and it was applied successfully for the determination of the miconazole in pure form and in commercial formulations, showing mean recoveries of 99.7-98.4%.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300005
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| Editor: |
Academia Brasileira de Ciências
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| Relação: |
10.1590/S0001-37652002000300005
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| Formato: |
text/html
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| Fonte: |
Anais da Academia Brasileira de Ciências v.74 n.3 2002
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| Direitos: |
info:eu-repo/semantics/openAccess
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